Water → HCID 11315915, Verbindung

HRID 1062623Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1062623
[CH3:1][C:2]([C:5]1[CH:10]=[CH:9][C:8]([C:11](=[O:19])[CH2:12][C:13]2[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=2)=[CH:7][CH:6]=1)([CH3:4])[CH3:3].[Br:20]Br.O>C(O)(=O)C>[BrH:20].[Br:20][CH:12]([C:13]1[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=1)[C:11]([C:8]1[CH:9]=[CH:10][C:5]([C:2]([CH3:1])([CH3:3])[CH3:4])=[CH:6][CH:7]=1)=[O:19]

Komponenten

5

Edukt 3

HCID 962WaterHCID 24408BromineHCID 104674521-[4-(1,1-DIMETHYLETHYL)PHENYL]-2-(4-PYRIDYL)ETHANONE

Produkt 1

HCID 11315915HCID 11315915, VerbindungAusbeute 119,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

1-[4-(1,1-Dimethylethyl)phenyl]-2-(4-pyridyl)ethanone (10 g, 39 mmol) was dissolved in acetic acid (40 mL) and bromine (2.0 mL, 39 mmol) was added. The mixture was stirred at 80° C. for 3 h. The reaction mixture was cooled with iced water and the precipitated crude crystals were collected by filtration. The crude crystals were washed with ethyl acetate to give the title compound (9.6 g, yield 81%).

Aufarbeitung

  1. customthe precipitated crude crystals
  2. filtrationwere collected by filtration
  3. washThe crude crystals were washed with ethyl acetate

Quellen und Nachweise

ORD-Eintrag
ord-f4bd80bc9c6b4b319f78dc9c59c4b919
Quelldatensatz
uspto-grants-2005_11
Patentnummer
US06962933B1

Notizen zur Reaktion

Wird geladen…