Water → Acifluorfen-methyl

HRID 1075317

Reaktionsgleichung

Reaktionsgleichung von HRID 1075317
[F:1][C:2]([F:24])([F:23])[C:3]1[CH:22]=[CH:21][C:6]([O:7][C:8]2[CH:9]=[CH:10][C:11]([N+:18]([O-:20])=[O:19])=[C:12]([CH:17]=2)[C:13]([O:15][CH3:16])=[O:14])=[CH:5][CH:4]=1.[Cl:25]Cl.O>CCOCC>[Cl:25][C:5]1[CH:4]=[C:3]([C:2]([F:23])([F:24])[F:1])[CH:22]=[CH:21][C:6]=1[O:7][C:8]1[CH:9]=[CH:10][C:11]([N+:18]([O-:20])=[O:19])=[C:12]([CH:17]=1)[C:13]([O:15][CH3:16])=[O:14]

Komponenten

5

Edukt 3

HCID 962WaterHCID 24526ChlorineHCID 13209694Methyl 2-nitro-5-[4-(trifluoromethyl)phenoxy]benzoate

Produkt 1

HCID 91642Acifluorfen-methyl

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

Methyl 5-(4-trifluoromethylphenoxy)-2-nitrobenzoate is stirred with a catalytic amount of ferric chloride. The reaction mixture was heated to 70° C. under a continuous stream of chlorine gas. After 2.5 hours, the mixture was taken up in ether, shaken with water and the organic phase was dried over MgSO4. The ether was evaporated to afford methyl 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitrobenzoate. NMR (CDCl3)δ8.2-7 (m,6) 4.0 (2,3). TLC (40% ether/hexane) Rf ≈.4.

Aufarbeitung

  1. dry with materialthe organic phase was dried over MgSO4
  2. customThe ether was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-c85e0659d8554c0b9334c310b60f0b5a
Quelldatensatz
uspto-grants-1983_07
Patentnummer
US04395570

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