Water → 1,2-Bis(3,4-dimethoxyphenyl)ethanone

HRID 1087287

Reaktionsgleichung

Reaktionsgleichung von HRID 1087287
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][C:12]([OH:14])=O)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].O.[C:16]1([O:24][CH3:25])[C:17](=[CH:20][CH:21]=[CH:22][CH:23]=1)[O:18][CH3:19]>>[CH3:10][O:9][C:8]1[CH:7]=[CH:6][C:5]([CH2:11][C:12]([C:22]2[CH:21]=[CH:20][C:17]([O:18][CH3:19])=[C:16]([O:24][CH3:25])[CH:23]=2)=[O:14])=[CH:4][C:3]=1[O:2][CH3:1]

Komponenten

4

Edukt 3

HCID 962WaterHCID 7043VeratroleHCID 7139(3,4-Dimethoxyphenyl)acetic acid

Produkt 1

HCID 2311111,2-Bis(3,4-dimethoxyphenyl)ethanoneAusbeute 60 %

Versuchsvorschrift

A warm solution of 3,4-dimethoxyphenylacetic acid (10 g) in veratrole (15 ml) was added to 200 g of polyphosphoric acid (PPA). After 24 hrs. at room temperature the acid mixture was added to cold water (800 ml) and the product was collected and recrystallized from aqueous ethanol. The recrystallized intermediate (9.5 g, 60% yield) had a melting point of 104°-105°.

Aufarbeitung

  1. customthe product was collected
  2. customrecrystallized from aqueous ethanol

Quellen und Nachweise

ORD-Eintrag
ord-39ca3b0eaeec40169d68941347309b1a
Quelldatensatz
uspto-grants-1991_07
Patentnummer
US05034544

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