Water → N-(5-{[2-(acetylamino)[1,3]thiazolo[5,4-b]pyridin-5-yl]oxy}-4-chloro-2-fluorophenyl)-2-chloro-3-(1-cyano-1-methylethyl)benzamide
Reaktionsgleichung
[CH3:16][N:17]([CH3:18])[CH:19]=[O:20].[CH3:51][N:52]([CH3:53])[C:54](=[O:55])[CH3:56].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][cH:9][c:10]1[C:11]([CH3:12])([CH3:13])[C:14]#[N:15].[Cl:45][C:46]([C:47]([Cl:48])=[O:49])=[O:50].[NH2:21][c:22]1[c:23]([F:43])[cH:24][c:25]([Cl:42])[c:26]([O:27][c:28]2[cH:29][cH:30][c:31]3[c:32]([n:33]2)[s:34][c:35]([NH:37][C:38]([CH3:39])=[O:40])[n:36]3)[cH:41]1.[OH2:44]>>[Cl:1][c:2]1[c:3]([C:4](=[O:6])[NH:21][c:22]2[c:23]([F:43])[cH:24][c:25]([Cl:42])[c:26]([O:27][c:28]3[cH:29][cH:30][c:31]4[c:32]([n:33]3)[s:34][c:35]([NH:37][C:38]([CH3:39])=[O:40])[n:36]4)[cH:41]2)[cH:7][cH:8][cH:9][c:10]1[C:11]([CH3:12])([CH3:13])[C:14]#[N:15]
