Bromide ion → 2-(4-fluorophenyl)-N-methyl-6-(methylsulfonamido)-5-(prop-1-en-2-yl)furo[2,3-b]pyridine-3-carboxamide
Reaktionsgleichung
[B:6]([O:7][CH:8]([CH3:9])[CH3:10])([O:11][CH:12]([CH3:13])[CH3:14])[O:15][CH:16]([CH3:17])[CH3:18].[Br-:1].[CH2:2]=[C:3]([CH3:4])[Mg+:5].[F:25][c:26]1[cH:27][cH:28][c:29](-[c:32]2[c:33]([C:47](=[O:48])[NH:49][CH3:50])[c:34]3[c:35]([n:36][c:37]([NH:41][S:42](=[O:43])(=[O:44])[CH3:45])[c:38]([I:40])[cH:39]3)[o:46]2)[cH:30][cH:31]1.[K+:19].[K+:20].[O-:21][C:22]([O-:23])=[O:24].[cH:51]1[cH:52][cH:53][c:54]([P:55]([Pd:56]([P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)([P:76]([c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)([c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)[c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)[P:95]([c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)([c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)[c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)([c:114]2[cH:115][cH:116][cH:117][cH:118][cH:119]2)[c:120]2[cH:121][cH:122][cH:123][cH:124][cH:125]2)[cH:126][cH:127]1>>[CH2:2]=[C:3]([CH3:4])[c:38]1[c:37]([NH:41][S:42](=[O:43])(=[O:44])[CH3:45])[n:36][c:35]2[c:34]([c:33]([C:47](=[O:48])[NH:49][CH3:50])[c:32](-[c:29]3[cH:28][cH:27][c:26]([F:25])[cH:31][cH:30]3)[o:46]2)[cH:39]1
