Morpholine → 5-Morpholinopyridin-3-amine

Temperatur

150 °C

diacetoxypalladium (20.76 mg, 0.09 mmol) was added to 5-bromopyridin-3-amine (160 mg, 0.92 mmol), morpholine (0.403 mL, 4.62 mmol) (9,9-dimethyl-9H-xanthene-4,5-diyl)bis(diphenylphosphine) (64.2 mg, 0.11 mmol) and cesium carbonate (603 mg, 1.85 mmol) in dioxane (5 mL). The resulting solution was stirred at 150 °C in the microwave for 30 minutes. The major product was the dimer. Rection abandoned.

ORD-Eintrag

ord-d5f70214ac20425bbba3af9e0d825482

Quelldatensatz

750 AstraZeneca ELN dataset

Originallink

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