Acetic Anhydride → [5-[4-(Dimethylamino)butyl]-2-furanyl]methyl ethanoate

HRID 1277866Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1277866
[CH3:1][N:2]([CH3:14])[CH2:3][CH2:4][CH2:5][CH2:6][C:7]1[O:11][C:10]([CH2:12][OH:13])=[CH:9][CH:8]=1.[C:15](OC(=O)C)(=[O:17])[CH3:16].C([O-])(=O)C.[Na+]>C1C=CC=CC=1.O>[C:15]([O:13][CH2:12][C:10]1[O:11][C:7]([CH2:6][CH2:5][CH2:4][CH2:3][N:2]([CH3:1])[CH3:14])=[CH:8][CH:9]=1)(=[O:17])[CH3:16]

Komponenten

6

Edukt 3

HCID 7918Acetic AnhydrideHCID 517045Sodium AcetateHCID 23452131HCID 23452131, Verbindung

Produkt 1

HCID 23452115[5-[4-(Dimethylamino)butyl]-2-furanyl]methyl ethanoate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 241BenzeneLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 5-[4 -(dimethylamino)butyl]-2-furanmethanol (4.9 g), acetic anhydride (25 g) and fused and powdered sodium acetate (10 g) in benzene (25 ml) was stirred at room temperature for 24 hr. The reaction was diluted with water (100 ml) and extracted with ethyl acetate. The combined extracts were distilled to afford a clear colourless oil b.p. 100°, 0.5 mm Hg. Found: C, 65.62; H, 9.03; N, 5.95. Calc. for C13H21NO3 ; C, 65.24; H, 8.85; N, 5.85%.

Aufarbeitung

  1. extractionextracted with ethyl acetate
  2. distillationThe combined extracts were distilled

Quellen und Nachweise

ORD-Eintrag
ord-df62e9c4986941ad9b2ffb019ab61ead
Quelldatensatz
uspto-grants-1981_07
Patentnummer
US04279819

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