1,2-Dichloroethane → (E)-N-((3-ethyl-1H-indol-2-yl)methyl)-N-methyl-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide

Reaktionsgleichung

C(Cl)CCl.[CH2:5]([C:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[NH:9][C:8]=1[CH2:16][NH:17][CH3:18])[CH3:6].Cl.[O:20]=[C:21]1[NH:30][C:29]2[N:28]=[CH:27][C:26](/[CH:31]=[CH:32]/[C:33]([OH:35])=O)=[CH:25][C:24]=2[CH2:23][CH2:22]1.C1C=CC2N(O)N=NC=2C=1.CCN(C(C)C)C(C)C>CN(C=O)C.O>[CH2:5]([C:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[NH:9][C:8]=1[CH2:16][N:17]([CH3:18])[C:33](=[O:35])/[CH:32]=[CH:31]/[C:26]1[CH:27]=[N:28][C:29]2[NH:30][C:21](=[O:20])[CH2:22][CH2:23][C:24]=2[CH:25]=1)[CH3:6]