Acetic Acid → (1R,2S,3R)-3-{1-[4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]piperidin-4-ylamino}cyclopentane-1,2-diol

Reaktionsgleichung

Cl.[NH2:2][C@@H:3]1[CH2:7][CH2:6][C@@H:5]([OH:8])[C@H:4]1[OH:9].CCN(C(C)C)C(C)C.[CH3:19][C:20]1([CH3:44])[CH2:29][CH2:28][C:27]([CH3:31])([CH3:30])[C:26]2[CH:25]=[C:24]([C:32]3[N:33]=[C:34]([N:37]4[CH2:42][CH2:41][C:40](=O)[CH2:39][CH2:38]4)[S:35][CH:36]=3)[CH:23]=[CH:22][C:21]1=2.C(O)(=O)C.C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[Na+].C(=O)([O-])O.[Na+]>C1COCC1.CN(C=O)C>[CH3:19][C:20]1([CH3:44])[CH2:29][CH2:28][C:27]([CH3:30])([CH3:31])[C:26]2[CH:25]=[C:24]([C:32]3[N:33]=[C:34]([N:37]4[CH2:42][CH2:41][CH:40]([NH:2][C@@H:3]5[CH2:7][CH2:6][C@@H:5]([OH:8])[C@H:4]5[OH:9])[CH2:39][CH2:38]4)[S:35][CH:36]=3)[CH:23]=[CH:22][C:21]1=2