Hydrochloric Acid → HCID 53705343, Verbindung

HRID 1415218Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1415218
[C:1]([CH:4]1[C:8](=[O:9])[CH2:7][CH2:6][C:5]1=[O:10])(=[O:3])[CH3:2].[Cl:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][C:19]=1[Cl:20])[CH:15]=O.N1CCOCC1.Cl>O.C(O)C>[Cl:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][C:19]=1[Cl:20])[CH:15]=[CH:2][C:1]([CH:4]1[C:8](=[O:9])[CH2:7][CH2:6][C:5]1=[O:10])=[O:3]

Komponenten

7

Edukt 4

HCID 313Hydrochloric AcidHCID 8083MorpholineHCID 227103,4-DichlorobenzaldehydeHCID 3364732-Acetyl-1,3-cyclopentanedione

Produkt 1

HCID 53705343HCID 53705343, VerbindungAusbeute 37,4 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

2-Acetyl-1,3-cyclopentanedione (3.13 g.) was treated with 3,4-dichlorobenzaldehyde (4.36 g.) in 140 ml. of ethanol under reflux for 4 hours in the presence of 5 ml. of morpholine. After cooling, the reaction mixture was poured into 150 ml. of water containing 7 ml. of conc. hydrochloric acid. Deposited crystals were separated by filtration and washed with water, and dried. 2-(3,4-Dichlorocinnamoyl)-1,3-cyclopentanedione (2.48 g., 37%) was obtained which showed mp. 190°- 191° C. after recrystallization from dioxane.

Aufarbeitung

  1. temperatureAfter cooling
  2. additionthe reaction mixture was poured into 150 ml
  3. customDeposited crystals were separated by filtration
  4. washwashed with water
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-0cc9c682c8d6438daabb77fa6f991bab
Quelldatensatz
uspto-grants-1977_01
Patentnummer
US04003936

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