Sodium Acetate → Furo[3,4-c]quinolin-3(1H)-one

HRID 1415715Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1415715
Cl[C:2]1[C:11]2[C:12](=[O:15])[O:13][CH2:14][C:10]=2[C:9]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[N:3]=1.C([O-])(=O)C.[Na+]>[Pd].C(O)(=O)C>[CH2:14]1[C:10]2[C:9]3[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=3[N:3]=[CH:2][C:11]=2[C:12](=[O:15])[O:13]1

Komponenten

5

Edukt 2

HCID 517045Sodium AcetateHCID 57030353HCID 57030353, Verbindung

Produkt 1

HCID 57183566Furo[3,4-c]quinolin-3(1H)-one

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

A mixture of 4-Chloro-furo[3,4-c]quinolin-3(1H)-one (500 mg), 10% Palladium on carbon (100 mg) and sodium acetate (500 mg) in 20 mL of acetic acid was hydrogenated at atmospheric pressure for 2 h. After filtration through celite, the solvent was removed in vacuo, and the residue was taken up in methylene chloride. After filtration the solvent was removed in vacuo to afford Furo[3,4-c]quinolin-3(1H)-one as a solid.

Aufarbeitung

  1. filtrationAfter filtration through celite
  2. customthe solvent was removed in vacuo
  3. filtrationAfter filtration the solvent
  4. customwas removed in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-d6252329efdd4e97a62e3d791eeaeef0
Quelldatensatz
uspto-grants-1999_06
Patentnummer
US05908932

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