1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide → trans-3-(3-Cyano-phenylcarbamoyl)-4-[3-(5-methyl-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridin-2-ylcarbamoyl)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester

Reaktionsgleichung

CN(C)CCCN=C=NCC.OC1C2N=NNC=2C=CC=1.C(N(CC)C(C)C)(C)C.[C:31]([O:35][C:36]([N:38]1[CH2:42][C@@H:41]([C:43](=[O:53])[NH:44][C:45]2[CH:50]=[CH:49][CH:48]=[C:47]([C:51]#[N:52])[CH:46]=2)[C@H:40]([C:54]2[CH:59]=[CH:58][CH:57]=[C:56]([C:60](O)=[O:61])[CH:55]=2)[CH2:39]1)=[O:37])([CH3:34])([CH3:33])[CH3:32].[CH3:63][N:64]1[CH2:69][CH2:68][C:67]2[N:70]=[C:71]([NH2:73])[S:72][C:66]=2[CH2:65]1>CC(N(C)C)=O.O>[C:31]([O:35][C:36]([N:38]1[CH2:39][C@@H:40]([C:54]2[CH:59]=[CH:58][CH:57]=[C:56]([C:60](=[O:61])[NH:73][C:71]3[S:72][C:66]4[CH2:65][N:64]([CH3:63])[CH2:69][CH2:68][C:67]=4[N:70]=3)[CH:55]=2)[C@H:41]([C:43](=[O:53])[NH:44][C:45]2[CH:50]=[CH:49][CH:48]=[C:47]([C:51]#[N:52])[CH:46]=2)[CH2:42]1)=[O:37])([CH3:33])([CH3:34])[CH3:32]