Hydroxide → Tert-butyl 3-{4-[({2',6'-dimethyl-4'-[2-(2-oxopyrrolidin-1-yl)ethoxy]biphenyl-3-yl}methyl)amino]-2-fluorophenyl}propanoate
Reaktionsgleichung
[CH3:1][c:2]1[c:3](-[c:18]2[cH:19][c:20]([CH2:24][N:25]([c:26]3[cH:27][c:28]([F:41])[c:29]([CH2:32][CH2:33][C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[cH:30][cH:31]3)[S:42]([c:43]3[cH:44][cH:45][cH:46][cH:47][c:48]3[N+:49]([O-:50])=[O:51])(=[O:52])=[O:53])[cH:21][cH:22][cH:23]2)[c:4]([CH3:17])[cH:5][c:6]([O:8][CH2:9][CH2:10][N:11]2[C:12](=[O:16])[CH2:13][CH2:14][CH2:15]2)[cH:7]1.[CH3:62][N:63]([CH3:64])[CH:65]=[O:66].[Li+:61].[OH-:60].[OH2:59].[SH:54][CH2:55][C:56]([OH:57])=[O:58]>>[CH3:1][c:2]1[c:3](-[c:18]2[cH:19][c:20]([CH2:24][NH:25][c:26]3[cH:27][c:28]([F:41])[c:29]([CH2:32][CH2:33][C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[cH:30][cH:31]3)[cH:21][cH:22][cH:23]2)[c:4]([CH3:17])[cH:5][c:6]([O:8][CH2:9][CH2:10][N:11]2[C:12](=[O:16])[CH2:13][CH2:14][CH2:15]2)[cH:7]1
