Acetic Acid → HCID 178489128, Verbindung

HRID 1576233

Reaktionsgleichung

Reaktionsgleichung von HRID 1576233
[C:1]1([C:9]([C:11]([C:13]2[CH:20]=[CH:19][C:16]([O:17][CH3:18])=[CH:15][CH:14]=2)=O)=O)[CH:8]=[CH:7][C:4]([O:5][CH3:6])=[CH:3][CH:2]=1.Cl.[NH2:22][NH:23][C:24]([NH2:26])=[O:25].C([O-])(=O)C.[Na+].C(O)(=O)C>O>[OH:25][C:24]1[N:23]=[N:22][C:11]([C:13]2[CH:20]=[CH:19][C:16]([O:17][CH3:18])=[CH:15][CH:14]=2)=[C:9]([C:1]2[CH:8]=[CH:7][C:4]([O:5][CH3:6])=[CH:3][CH:2]=2)[N:26]=1

Komponenten

6

Edukt 4

HCID 176Acetic AcidHCID 11236Semicarbazide hydrochlorideHCID 710434,4'-DimethoxybenzilHCID 517045Sodium Acetate

Produkt 1

HCID 178489128HCID 178489128, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

Two moles, 540 g., of anisil (4,4'-dimethoxybenzil), 222 g. (2 moles) of semicarbazide hydrochloride, 180 g. (2.2 moles) of sodium acetate and 2.5 liters of acetic acid were refluxed overnight. The cooled reaction mixture was poured into 5 liters of water. The crude solid product was collected by filtration, washed with water and recrystallized from acetic acid. The yield was 434 g. of 3-hydroxy-5,6-bis(4-methoxyphenyl)-1,2,4-triazine, mp about 272°-274°C.

Aufarbeitung

  1. customThe cooled reaction mixture
  2. filtrationThe crude solid product was collected by filtration
  3. washwashed with water
  4. customrecrystallized from acetic acid

Quellen und Nachweise

ORD-Eintrag
ord-7f20420cb8c44c17993d95e43c8e8bdc
Quelldatensatz
uspto-grants-1976_09
Patentnummer
US03979516

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