Peracetic Acid → 1,5-Methano-3H-cyclopent[c]oxepin-3-one, octahydro-

HRID 1576540

Reaktionsgleichung

Reaktionsgleichung von HRID 1576540
[C:1]([O:4]O)(=[O:3])[CH3:2].C([O-])(=O)C.[Na+].[CH:11]12[CH2:21][CH:17](C(=O)C1)[CH:16]1[CH:12]2[CH2:13][CH2:14][CH2:15]1>C(O)(=O)C.ClCCl>[CH:11]12[CH2:21][CH:17]([O:4][C:1](=[O:3])[CH2:2]1)[CH:16]1[CH:12]2[CH2:13][CH2:14][CH2:15]1

Komponenten

6

Edukt 3

HCID 6585Peracetic AcidHCID 965094,7-Methano-5H-inden-5-one, octahydro-HCID 517045Sodium Acetate2×

Produkt 1

HCID 1083601,5-Methano-3H-cyclopent[c]oxepin-3-one, octahydro-

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 176Acetic AcidLösungsmittelHCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

18 g of a 50 % peracetic acid solution in acetic acid containing 1 g of sodium acetate were added to a stirred mixture of 15 g of tricyclo[5.2.1.02,6 ]decane-8-one (which can be purchased from Ruhrchemie, Bruchstrasse, D-42 Oberhausen Holten, West Germany) and 9 g of anhydrous sodium acetate in 60 g of dichloromethane. The temperature of the reaction mixture was kept at 20°-25° by external cooling by means of a ice-water bath during the whole addition, then it was kept at this value during 48 hours while stirring.

Aufarbeitung

  1. customwas kept at 20°-25°
  2. temperatureby external cooling by means of a ice-water bath during the whole addition

Quellen und Nachweise

ORD-Eintrag
ord-2a81ae180fb44228ac443efbfe7440b9
Quelldatensatz
uspto-grants-1976_09
Patentnummer
US03981892

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