Reaktionsgleichung
[N:1](=[C:3]([CH2:7][CH2:8][CH3:9])[C:4](=O)[CH3:5])O.[CH3:10][C:11](=O)[CH2:12][CH2:13][CH2:14][CH3:15].[N:17](Cl)=O.N=C=O>[Zn].C(O)(=O)C>[CH3:10][C:11]1[C:12]([CH2:13][CH2:14][CH3:15])=[N:17][C:4]([CH3:5])=[C:3]([CH2:7][CH2:8][CH3:9])[N:1]=1Komponenten
Edukt 4
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
5 c. 2,5-Dimethyl-3,6-dipropyl-pyrazine was prepared by first forming 3-oximino-2-hexanone by reacting 2 -hexanone with nitrosyl chloride according to the method of BOUVEAULT, Bull. [3] 31, 1163 (1904). The autocondensation of two molecules of the imino-ketone in the presence of zinc and acetic acid [according to the method described in Chimia 11, 310 (1957)] yielded 2,5-dimethyl-3,6-dipropyl-pyrazine which had a b.p. of 109°-110°C./10 mm. Hg. 5 d. 2,5-Dimethyl-3,6-diisopropyl-pyrazine was prepared by first forming 4-methyl-3-oximino-2-pentanone by reacting 4-methyl-2-pentanone with nitrosyl chloride according to the method of BOUVEAULT, Bull. [3] 31, 1163 (1904). The autocondensation of two moles of the imino-ketone in the presence of zinc and acetic acid [according to the method described in Chimia 11, 310 (1957)] yielded 2,5-Dimethyl-3,6-diisopropyl-pyrazine which had a b.p. of 91°C./8 mm. Hg.
Quellen und Nachweise
- ORD-Eintrag
- ord-ce9f3c81ca2640528b8f3e1348166101
- Quelldatensatz
- uspto-grants-1976_01
- Patentnummer
- US03931246
Verknüpfte Notizen
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