2-Chloroethanol → Dithiaoctanediol

HRID 1583271

Reaktionsgleichung

Reaktionsgleichung von HRID 1583271
[CH2:1]([SH:4])[CH2:2][SH:3].[CH3:5][OH:6].[CH3:7][O-].[Na+].[CH2:10](Cl)[CH2:11][OH:12]>>[CH2:11]([OH:12])[CH2:10][S:3][CH2:2][CH2:1][S:4][CH2:7][CH2:5][OH:6]

Komponenten

5

Edukt 4

HCID 342-ChloroethanolHCID 887MethanolHCID 109021,2-EthanedithiolHCID 10942334Sodium Methoxide

Produkt 1

HCID 78904Dithiaoctanediol

Versuchsvorschrift

In an ice bath, 25 g of dithioglycol was stirred and thereto, was added dropwise 1.1 equivalent of a methanol solution of sodium methoxide. Further, 44 g of ethylene chlorohydrin was added dropwise thereto. After the conclusion of the dropwise addition, the reaction mixture was allowed to stand for 10 hours at a room temperature. Then, sodium chloride deposited was removed by filtration, and the resulting filtrate was concentrated. The thus obtained white crystals were recrystallized from acetone. Melting Point 65° C., Yield 25 g.

Aufarbeitung

  1. additionAfter the conclusion of the dropwise addition
  2. customThen, sodium chloride deposited was removed by filtration
  3. concentrationthe resulting filtrate was concentrated
  4. customThe thus obtained white crystals were recrystallized from acetone

Quellen und Nachweise

ORD-Eintrag
ord-2f4cb4a66e9242ea8816a9d8bece51dd
Quelldatensatz
uspto-grants-1985_11
Patentnummer
US04551419

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