Bromine → HCID 70456026, Verbindung

HRID 1589298Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1589298
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([S:9][CH3:10])[CH:6]=[CH:5][C:4]=1[C:11]1[N:20]=[C:14]2[C:15](=[O:19])[NH:16][CH2:17][CH:18]=[C:13]2[N:12]=1.C([O-])(=[O:23])C.[Na+].BrBr>C(O)(=O)C>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([S:9]([CH3:10])=[O:23])[CH:6]=[CH:5][C:4]=1[C:11]1[N:20]=[C:14]2[C:15](=[O:19])[NH:16][CH2:17][CH:18]=[C:13]2[N:12]=1

Komponenten

5

Edukt 3

HCID 24408BromineHCID 517045Sodium AcetateHCID 70455630HCID 70455630, Verbindung

Produkt 1

HCID 70456026HCID 70456026, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel2×

Versuchsvorschrift

0.3 g of 2-(2-methoxy-4-methylmercapto-phenyl)-5H-imidazo[4,5-c]pyridin-4-one were suspended in 10 ml of 50% acetic acid, and 0.2 g of anhydrous sodium acetate were added thereto. 0.15 g of bromine, dissolved in 2 ml of glacial acetic acid, was added dropwise to the mixture, while stirring. After the reaction had ended the mixture was poured over ice, and the precipitate thus obtained was recrystallized from ethanol. Melting point: 267°-272° C. (decomposition).

Aufarbeitung

  1. additionwas added dropwise to the mixture
  2. additionwas poured over ice
  3. customthe precipitate thus obtained
  4. customwas recrystallized from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-fc11ee5874bc4708a1c6d4bce9ae20f3
Quelldatensatz
uspto-grants-1986_02
Patentnummer
US04568680

Notizen zur Reaktion

Wird geladen…