4-Bromoaniline → 4-bromophenylcyanamide

HRID 1593565Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1593565
[N:1]#[C:2]Br.[Br:4][C:5]1[CH:11]=[CH:10][C:8]([NH2:9])=[CH:7][CH:6]=1>C(OCC)C>[Br:4][C:5]1[CH:11]=[CH:10][C:8]([NH:9][C:2]#[N:1])=[CH:7][CH:6]=1

Komponenten

4

Edukt 2

HCID 78074-BromoanilineHCID 10476Cyanogen Bromide

Produkt 1

HCID 122959414-bromophenylcyanamideAusbeute 92 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

A mixture of cyanogen bromide (5.0 g, 47 mmol), and 4-bromoaniline (17.8 g, 103.4 mmol) in diethylether (150 mL) was stirred for 3 days under nitrogen atmosphere. The reaction was filtered, and the filtrate was concentrated in vacuo at room temperature to give 4-bromophenylcyanamide (8.5 g, 92%) as an off white solid.

Aufarbeitung

  1. filtrationThe reaction was filtered
  2. concentrationthe filtrate was concentrated in vacuo at room temperature

Quellen und Nachweise

ORD-Eintrag
ord-b9e1ab41dad44ac7b28c4b07c2a3f48f
Quelldatensatz
uspto-grants-2007_11
Patentnummer
US07297713B2

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