3-(4-Methoxyphenyl)-2-phenylprop-2-enoic acid → 3-(4-Methoxyphenyl)-2-phenylpropionic acid

HRID 1935734

Reaktionsgleichung

Reaktionsgleichung von HRID 1935734
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]=[C:10]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:11]([OH:13])=[O:12])=[CH:5][CH:4]=1>[Pd].C(O)(=O)C>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:9][CH:10]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:11]([OH:13])=[O:12])=[CH:7][CH:8]=1

Komponenten

4

Edukt 1

HCID 2366983-(4-Methoxyphenyl)-2-phenylprop-2-enoic acid

Produkt 1

HCID 977393-(4-Methoxyphenyl)-2-phenylpropionic acid

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

Palladium on activated carbon (10% wt., 2.77 g) was added to a solution of 3-(4-methoxyphenyl)-2-phenylacrylic acid (27.7 g, 0.11 mol) in acetic acid (1000 ml). The mixture was hydrogenated at ambient temperature. The mixture was filtered through Celite, and the solvent was evaporated. The product was recrystallized from a small amount of ethyl acetate. Melting point 220-221° C.

Aufarbeitung

  1. customwas hydrogenated at ambient temperature
  2. filtrationThe mixture was filtered through Celite
  3. customthe solvent was evaporated
  4. customThe product was recrystallized from a small amount of ethyl acetate

Quellen und Nachweise

ORD-Eintrag
ord-1882dce487974d0793678a129d3179de
Quelldatensatz
uspto-grants-2002_05
Patentnummer
US06388090B2

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