Sulfuric Acid → HCID 70436618, Verbindung

HRID 1995046Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1995046
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]([NH:9][CH:10]1[C:21](=[O:22])[N:12]2[C:13]([C:18]([OH:20])=[O:19])=[C:14](Cl)[CH2:15][S:16][C@H:11]12)=[O:8].S([O-])([O-])(=O)=O.[K+].[K+].S(=O)(=O)(O)O>[I-].C([N+](CCCC)(CCCC)CCCC)CCC.[Hg].[Pt]>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]([NH:9][CH:10]1[C:21](=[O:22])[N:12]2[C:13]([C:18]([OH:20])=[O:19])=[CH:14][CH2:15][S:16][C@H:11]12)=[O:8]

Komponenten

7

Edukt 3

HCID 1118Sulfuric AcidHCID 24507Potassium SulfateHCID 70437070HCID 70437070, Verbindung

Produkt 1

HCID 70436618HCID 70436618, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 23931MercuryKatalysatorHCID 23939PlatinumKatalysatorHCID 67553Tetrabutylammonium IodideKatalysator

Versuchsvorschrift

Fifty ml. of working fluid was prepared, containing 6.4 mg./ml. of 7-(thien-2-ylacetamido)-3-chloro-3-cephem-4-carboxylic acid in 0.25 molar pH 8 McIlvaine buffer containing 0.0375 molar tetrabutylammonium iodide. The McIlvaine buffer was prepared according to McIlvaine's article at Anal. Chem. 28, 1179 (1956). The measured pH of the working fluid was 7.3. It was transferred to the cathode compartment of an electrolysis cell having a mercury ring working electrode and a stirrer. The circular auxiliary electrode compartment was suspended over the mercury pool, and consisted of a platinum wire in toroidal shape over a 4% agar gel supported by a medium porosity sintered glass frit. The auxiliary fluid was saturated aqueous potassium sulfate. The cell was stoppered, and a deaerating frit, pH electrode, reference electrode and a delivery tube through which 2 N sulfuric acid could be added were installed. The reference electrode was a Beckman fiber-junction saturated calomel electrode.

Aufarbeitung

  1. customwas prepared
  2. additioncontaining 6.4 mg
  3. customThe McIlvaine buffer was prepared

Quellen und Nachweise

ORD-Eintrag
ord-b2755ad35b734f4daa639615b4f211b1
Quelldatensatz
uspto-grants-1983_09
Patentnummer
US04402803

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