Formic Acid → 3-(Formylamino)benzoic acid

HRID 2332

Reaktionsgleichung

Reaktionsgleichung von HRID 2332
[C:1](OC(=O)C)(=[O:3])C.C(O)=O.[NH2:11][C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][CH:20]=1)[C:15]([OH:17])=[O:16]>O>[CH:1]([NH:11][C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][CH:20]=1)[C:15]([OH:17])=[O:16])=[O:3]

Komponenten

5

Edukt 3

HCID 284Formic AcidHCID 74193-Aminobenzoic AcidHCID 7918Acetic Anhydride

Produkt 1

HCID 152489873-(Formylamino)benzoic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

Acetic anhydride (76 ml) was added to 98% formic acid (130 ml) and the mixture stirred at r.t. 30 min, then 3-aminobenzoic acid (15 g, 109.5 mmol) added. The mixture was stirred at r.t. for 1 h, then water (1.3 L) added and stirring continued overnight. The resultant white precipitate was collected, washed with water and dried in vacuo over P2O5 (15.4 g, 85%).

Aufarbeitung

  1. stirringThe mixture was stirred at r.t. for 1 h
  2. stirringstirring continued overnight
  3. customThe resultant white precipitate was collected
  4. washwashed with water
  5. dry with materialdried in vacuo over P2O5 (15.4 g, 85%)

Quellen und Nachweise

ORD-Eintrag
ord-5570e335404a45e8bde112385306c6b2
Quelldatensatz
uspto-grants-1998_03
Patentnummer
US05728829

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