Acetic Acid → 1,2,4-Triazolo(4,3-b)(1,2,4)triazine, 7-(4-methoxyphenyl)-

HRID 237086

Reaktionsgleichung

Reaktionsgleichung von HRID 237086
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]([CH:11]=O)=O)=[CH:5][CH:4]=1.[NH2:13][C:14]1[N:18]([NH2:19])[CH:17]=[N:16][N:15]=1.C([O-])(=O)C.[Na+].C(O)(=O)C>O>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:11]=[N:19][N:18]3[CH:17]=[N:16][N:15]=[C:14]3[N:13]=2)=[CH:5][CH:4]=1

Komponenten

6

Edukt 4

HCID 176Acetic AcidHCID 70643(4-Methoxyphenyl)glyoxalHCID 517045Sodium AcetateHCID 5671443,4-Diamino-1,2,4-triazole

Produkt 1

HCID 30545031,2,4-Triazolo(4,3-b)(1,2,4)triazine, 7-(4-methoxyphenyl)-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A solution of 9.1 g. of p-methoxyphenylglyoxal, 6.7 g. of 3,4-diamino-4H-1,2,4-triazole and 4.1 g. of sodium acetate in 90 ml. of 67% acetic acid is heated on a steam bath for 1/2 hour. Water is added and heating is continued until crystals separate. The mixture is cooled and filtered. The precipitate is washed with water, ethanol and then hexane giving the desired product as yellow plates, m.p. 282.5°-284.5° C.

Aufarbeitung

  1. temperatureheating
  2. customseparate
  3. temperatureThe mixture is cooled
  4. filtrationfiltered
  5. washThe precipitate is washed with water, ethanol

Quellen und Nachweise

ORD-Eintrag
ord-3ee8d8310eaf43c7b4bc3e932185a9a1
Quelldatensatz
uspto-grants-1979_06
Patentnummer
US04159375

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