Sodium Hydroxide → Maltol

HRID 25909

Reaktionsgleichung

Reaktionsgleichung von HRID 25909
CO[CH:3]1[O:8][CH:7]([CH3:9])[C:6](=[O:10])[CH:5]=[CH:4]1.ClCl.[OH-:13].[Na+]>C(O)(=O)C.O>[CH3:9][C:7]1[O:8][CH:3]=[CH:4][C:5](=[O:13])[C:6]=1[OH:10]

Komponenten

6

Edukt 3

HCID 14798Sodium HydroxideHCID 24526ChlorineHCID 130117926-Methoxy-2-methyl-2H-pyran-3(6H)-one

Produkt 1

HCID 8369Maltol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 176Acetic AcidLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

A solution of 6-methoxy-2-methyl-2H-pyran-3(6H)-one (0.01 mole) in 20 ml of acetic acid was treated with gaseous chlorine (0.01 mole) at room temperature. The reaction mixture was then heated to reflux for about one hour, cooled to room temperature, diluted with 20 ml of water, the pH adjusted with 50% NaOH solution to 7.0 and the reaction mixture extracted with chloroform. The chloroform extract was concentrated to yield maltol which was recrystallized from methanol to give the pure product (56%), mp 159.5°-160.5° C.

Aufarbeitung

  1. temperatureThe reaction mixture was then heated
  2. temperatureto reflux for about one hour
  3. extractionthe reaction mixture extracted with chloroform
  4. extractionThe chloroform extract
  5. concentrationwas concentrated

Quellen und Nachweise

ORD-Eintrag
ord-7f1252b2941e457884750f3b255f5eb4
Quelldatensatz
uspto-grants-1979_04
Patentnummer
US04147705

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