Isocyanic acid → 3,6-Dibutyl-2,5-dimethylpyrazine

HRID 267655

Reaktionsgleichung

Reaktionsgleichung von HRID 267655
[N:1](=[C:3]([CH2:7][CH2:8][CH2:9][CH3:10])[C:4](=O)[CH3:5])O.[CH3:11][C:12](=O)[CH2:13][CH2:14][CH2:15][CH2:16][CH3:17].[N:19](Cl)=O.N=C=O>[Zn].C(O)(=O)C>[CH3:11][C:12]1[C:13]([CH2:14][CH2:15][CH2:16][CH3:17])=[N:19][C:4]([CH3:5])=[C:3]([CH2:7][CH2:8][CH2:9][CH3:10])[N:1]=1

Komponenten

7

Edukt 4

HCID 6347Isocyanic acidHCID 80512-HeptanoneHCID 17601Nitrosyl chlorideHCID 57349923HCID 57349923, Verbindung

Produkt 1

HCID 6012253,6-Dibutyl-2,5-dimethylpyrazine

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23994ZincKatalysatorHCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

e. 2,5-Dimethyl-3,6-dibutyl-pyrazine was prepared by first forming 3-oximino-2-heptanone by reacting 2-heptanone with nitrosyl chloride according to the method of BOUVEAULT, Bull. [3] 31, 1163 (1904). The autocondensation of two moles of the imino-ketone in the presence of zinc and acetic acid [according to the method described in Chimia 11, 310 (1957)] yielded 2,5-dimethyl-3,6-dibutyl-pyrazine which had a b.p. of 18°C./0.002 mm. Hg.

Quellen und Nachweise

ORD-Eintrag
ord-c273c6ffc3614cacb981034d91f88874
Quelldatensatz
uspto-grants-1976_03
Patentnummer
US03943260

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