Benzene, [1-[(trimethylsilyl)oxy]ethenyl]- → 2-Phenylacetophenone

Temperatur

0 °C

0.97 mmol of (1-phenylethenyl)oxytrimethylsilane was placed in a 20-ml flask, followed by the addition of 3 ml of pyridine as a solvent. 1.3 mmol of benzenediazonium tetrafluoroborate was added to the flask. The resulting mixture was stirred at 0° C. in a nitrogen atmosphere for 2 hours. The reaction mixture was diluted with diethyl ether and washed with 1.5 N hydrochloric acid, water and a saturated aqueous solution of common salt, successively. The organic phase was dried over magnesium sulfate and distilled under a reduced pressure to remove the solvent. The obtained oily mixture was subjected to silica gel thin-layer chromatography to obtain 0.68 mmol of benzyl phenyl ketone.

1. washwashed with 1.5 N hydrochloric acid, water
2. dry with materialThe organic phase was dried over magnesium sulfate
3. distillationdistilled under a reduced pressure
4. customto remove the solvent

ORD-Eintrag

ord-515947eac51f4236977fc35b3ddaaa6e

Quelldatensatz

uspto-grants-1990_01

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US04892936