Water → 6-Phenylnicotinic acid

HRID 363184

Reaktionsgleichung

Reaktionsgleichung von HRID 363184
[C:1]1([C:7]2[CH:12]=[CH:11][C:10]([CH3:13])=[CH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Mn]([O-])(=O)(=O)=[O:15].[K+].[OH2:20]>>[C:1]1([C:7]2[CH:12]=[CH:11][C:10]([C:13]([OH:15])=[O:20])=[CH:9][N:8]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Komponenten

4

Edukt 3

HCID 962WaterHCID 474675-Methyl-2-phenylpyridineHCID 516875Potassium Permanganate

Produkt 1

HCID 1201186-Phenylnicotinic acid

Versuchsvorschrift

A suspension of 2-phenyl-5-methyl pyridine (1.03 g, 6.09 mmol) and potassium permanganate (2.89 g, 18.3 mmol), in water (25 mL) was heated at reflux for 2 hours. The reaction was allowed to cool to ambient temperature and filtered through celite to remove the solids. Acetic acid (1 mL) was added to the colourless filtrate and the product was collected as a white solid by filtration.

Aufarbeitung

  1. temperatureat reflux for 2 hours
  2. filtrationfiltered through celite
  3. customto remove the solids
  4. additionAcetic acid (1 mL) was added to the colourless filtrate
  5. filtrationthe product was collected as a white solid by filtration

Quellen und Nachweise

ORD-Eintrag
ord-6e644e5ebedd4852bf22e76bd7adb84c
Quelldatensatz
uspto-grants-1999_02
Patentnummer
US05872136

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