Chlorine → HCID 19937923, Verbindung

HRID 36801Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 36801
[CH3:1][S:2]([NH:5][C:6]1[CH:7]=[CH:8][C:9]([F:18])=[C:10]([CH:17]=1)[NH:11][C:12](=[O:16])[O:13][CH2:14][CH3:15])(=[O:4])=[O:3].[Cl:19]Cl>C(O)(=O)C.O>[Cl:19][C:7]1[C:6]([NH:5][S:2]([CH3:1])(=[O:3])=[O:4])=[CH:17][C:10]([NH:11][C:12](=[O:16])[O:13][CH2:14][CH3:15])=[C:9]([F:18])[CH:8]=1

Komponenten

5

Edukt 2

HCID 24526ChlorineHCID 19937925Ethyl 5-methylsulfonylamino-2-fluorocarbanilate

Produkt 1

HCID 19937923HCID 19937923, VerbindungAusbeute 90 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 176Acetic AcidLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

80.6 g (292 mmol) of ethyl 5-methylsulfonylamino-2-fluorocarbanilate was dissolved in a mixture of 1075 ml of acetic acid and 100 ml of water, and chlorine gas was added to the resultant solution at a temperature of not higher than 25° C. until the starting material disappeared. After the reaction was completed, the surplus chlorine gas was removed by blowing nitrogen gas thereinto, and hexane was added. The precipitates crystals were filtered out to obtain 81.4 g of the objective product (yield: 90%) in the form of yellow crystals.

Aufarbeitung

  1. customthe surplus chlorine gas was removed
  2. additionhexane was added
  3. filtrationThe precipitates crystals were filtered out

Quellen und Nachweise

ORD-Eintrag
ord-37edf1745ff24e0d9bc9313ecf7b3020
Quelldatensatz
uspto-grants-1995_05
Patentnummer
US05416236

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