Water → (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl acetate

HRID 37262

Reaktionsgleichung

Reaktionsgleichung von HRID 37262
[OH:1][CH2:2][CH:3]1[CH2:7][O:6][C:5]([CH3:9])([CH3:8])[O:4]1.N1C=CC=CC=1.[C:16](OC(=O)C)(=[O:18])[CH3:17].O>ClCCl.C(OCC)(=O)C>[C:16]([O:1][CH2:2][CH:3]1[CH2:7][O:6][C:5]([CH3:9])([CH3:8])[O:4]1)(=[O:18])[CH3:17]

Komponenten

7

Edukt 4

HCID 962WaterHCID 1049PyridineHCID 7528SolketalHCID 7918Acetic Anhydride

Produkt 1

HCID 252333(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl acetateAusbeute 85,4 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 6344DichloromethaneLösungsmittelHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

To a mixture of 4-hydroxymethyl-2,2-dimethyl-1,3-dioxolane (5.35 g) and pyridine (15.65 g) in dichloromethane (200 ml) was added acetic anhydride (20.56 g), and the mixture was stirred at ambient temperature for 12 hours. The mixture was poured into a mixture of water and ethyl acetate. The organic layer was separated, washed with saturated aqueous sodium hydrogen carbonate and brine successively, dried over magnesium sulfate, and evaporated in vacuo to give 4-acetoxymethyl-2,2-dimethyl-1,3-dioxolane (6.02 g).

Aufarbeitung

  1. customThe organic layer was separated
  2. washwashed with saturated aqueous sodium hydrogen carbonate and brine successively
  3. dry with materialdried over magnesium sulfate
  4. customevaporated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-d89cf0c6c2db4b6a9bf43154be9933c2
Quelldatensatz
uspto-grants-1995_05
Patentnummer
US05420122

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