Acetic Acid → (R)-4-[5-[[2-[[tert-Butyldimethylsilyl)oxy]-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl]amino]pentyl]-N-[[1,6-diethyl-4-[(tetrahydro-2H-pyran-4-yl)amino]-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl]benzamide

Reaktionsgleichung

[BH3-]C#N.[Na+].[NH2:5][CH2:6][C@@H:7]([C:16]1[CH:25]=[CH:24][C:23]([OH:26])=[C:22]2[C:17]=1[CH:18]=[CH:19][C:20](=[O:27])[NH:21]2)[O:8][Si:9]([C:12]([CH3:15])([CH3:14])[CH3:13])([CH3:11])[CH3:10].[CH2:28]([N:30]1[C:34]2=[N:35][C:36]([CH2:62][CH3:63])=[C:37]([CH2:46][NH:47][C:48](=[O:61])[C:49]3[CH:54]=[CH:53][C:52]([CH2:55][CH2:56][CH2:57][CH2:58][CH:59]=O)=[CH:51][CH:50]=3)[C:38]([NH:39][CH:40]3[CH2:45][CH2:44][O:43][CH2:42][CH2:41]3)=[C:33]2[CH:32]=[N:31]1)[CH3:29].C(O)(=O)C.C([O-])(O)=O.[Na+]>C1COCC1.CCOC(C)=O.O>[Si:9]([O:8][C@H:7]([C:16]1[CH:25]=[CH:24][C:23]([OH:26])=[C:22]2[C:17]=1[CH:18]=[CH:19][C:20](=[O:27])[NH:21]2)[CH2:6][NH:5][CH2:59][CH2:58][CH2:57][CH2:56][CH2:55][C:52]1[CH:51]=[CH:50][C:49]([C:48]([NH:47][CH2:46][C:37]2[C:38]([NH:39][CH:40]3[CH2:41][CH2:42][O:43][CH2:44][CH2:45]3)=[C:33]3[CH:32]=[N:31][N:30]([CH2:28][CH3:29])[C:34]3=[N:35][C:36]=2[CH2:62][CH3:63])=[O:61])=[CH:54][CH:53]=1)([C:12]([CH3:15])([CH3:14])[CH3:13])([CH3:11])[CH3:10]