Dibenzylamine → n,n-Dibenzylformamide

HRID 437859

Reaktionsgleichung

Reaktionsgleichung von HRID 437859
[CH2:1]([NH:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:16](OC(=O)C)(=[O:18])C>C(O)=O>[CH:16]([N:8]([CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:18]

Komponenten

4

Edukt 2

HCID 7656DibenzylamineHCID 7918Acetic Anhydride

Produkt 1

HCID 221415n,n-Dibenzylformamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 284Formic AcidLösungsmittel

Versuchsvorschrift

To an ice-cold and vigorously stirred solution of dibenzylamine (918 g.) in 98% formic acid (105 ml.) is added dropwise, over 45 minutes, acetic anhydride (35 ml.). The resulting mixture is stirred for one hour at room temperature, then diluted with ice water (40 ml.) and kept overnight at 15° C. The solution is evaporated in vacuo to dryness and the residue extracted with ether. The ethereal solution is washed with water, dried over magnesium sulfate, filtered, and evaporated in vacuo to yield N-formyl-dibenzylamine (9.9 g.) as a white solid, m.p. 53°-54.5° C.

Aufarbeitung

  1. waitkept overnight at 15° C
  2. customThe solution is evaporated in vacuo to dryness
  3. extractionthe residue extracted with ether
  4. washThe ethereal solution is washed with water
  5. dry with materialdried over magnesium sulfate
  6. filtrationfiltered
  7. customevaporated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-8cf0564eba464f84a985114127fa7ac5
Quelldatensatz
uspto-grants-1977_06
Patentnummer
US04032521

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