1-Hydroxybenzotriazole → (E)-3-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl]-N-[2-oxo-3-(3,4,5-trifluorophenyl)piperidin-1-yl]acrylamide

Reaktionsgleichung

C1C=CC2N(O)N=NC=2C=1.C(N(C(C)C)CC)(C)C.[CH3:20][O:21][C:22]1[N:27]=[C:26](/[CH:28]=[CH:29]/[C:30]([OH:32])=O)[CH:25]=[CH:24][C:23]=1[N:33]1[CH:37]=[C:36]([CH3:38])[N:35]=[CH:34]1.[NH2:39][N:40]1[CH2:45][CH2:44][CH2:43][CH:42]([C:46]2[CH:51]=[C:50]([F:52])[C:49]([F:53])=[C:48]([F:54])[CH:47]=2)[C:41]1=[O:55]>CN(C=O)C.C(OCC)(=O)C.O.C(Cl)CCl>[CH3:20][O:21][C:22]1[N:27]=[C:26](/[CH:28]=[CH:29]/[C:30]([NH:39][N:40]2[CH2:45][CH2:44][CH2:43][CH:42]([C:46]3[CH:47]=[C:48]([F:54])[C:49]([F:53])=[C:50]([F:52])[CH:51]=3)[C:41]2=[O:55])=[O:32])[CH:25]=[CH:24][C:23]=1[N:33]1[CH:37]=[C:36]([CH3:38])[N:35]=[CH:34]1