Acetic Acid → 2-Methoxy-4-(methylamino)-5-nitrophenol

HRID 579691Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 579691
[CH3:1][NH:2][C:3]1[CH:8]=[C:7]2[O:9][CH2:10][O:11][C:6]2=[CH:5][C:4]=1[N+:12]([O-:14])=[O:13].C[O-].[Na+].C(O)(=O)C>CO.O>[CH3:10][O:9][C:7]1[CH:8]=[C:3]([NH:2][CH3:1])[C:4]([N+:12]([O-:14])=[O:13])=[CH:5][C:6]=1[OH:11]

Komponenten

6

Edukt 3

HCID 176Acetic AcidHCID 10942334Sodium MethoxideHCID 13742671N-methyl-6-nitro-1,3-dioxaindan-5-amine

Produkt 1

HCID 137426772-Methoxy-4-(methylamino)-5-nitrophenol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittel2×HCID 962WaterLösungsmittel

Versuchsvorschrift

A solution of 0.1 mol (19.6 g) of 2-methylamino-4,5-methylenedioxy-1-nitrobenzene, prepared according to Example 3, in 80 ml of a 30% strength solution of sodium methylate in methanol is brought for 15 minutes to the refluxing temperature of the methanol. The reaction medium is diluted with 500 ml of water. After the filtrate has been neutralized with acetic acid, the expected product precipitates.

Aufarbeitung

  1. customthe expected product precipitates

Quellen und Nachweise

ORD-Eintrag
ord-9264688154a34f7aa552f22b3eac3875
Quelldatensatz
uspto-grants-1988_06
Patentnummer
US04749379

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