Acetic Acid → N-Acetyl-2,6-xylidine

HRID 579968

Reaktionsgleichung

Reaktionsgleichung von HRID 579968
[NH2:1][C:2]1[C:3]([CH3:9])=[CH:4][CH:5]=[CH:6][C:7]=1[CH3:8].[C:10](OC(=O)C)(=[O:12])[CH3:11].C(O)(=O)C>O>[C:10]([NH:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH3:9])(=[O:12])[CH3:11]

Komponenten

5

Edukt 3

HCID 176Acetic AcidHCID 68962,6-DimethylanilineHCID 7918Acetic Anhydride

Produkt 1

HCID 16616N-Acetyl-2,6-xylidineAusbeute 92,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

To 25 ml of 2,6-xylidine (0.20 mole) was added slowly a mixture of 25 ml of acetic anhydride (0.26 mole) and 25 ml of acetic acid (0.44 mole) under stirring at room temperature. The mixture was stirred for 30 minutes at room temperature and, then, diluted with water. The crystalline precipitate was collected by filtration to give 30.1 g (91%) of the title compound (m.p. 182°-184° C.; colorless needles).

Aufarbeitung

  1. stirringThe mixture was stirred for 30 minutes at room temperature
  2. filtrationThe crystalline precipitate was collected by filtration

Quellen und Nachweise

ORD-Eintrag
ord-65932ea602734fb29d525f9b6ee3ee14
Quelldatensatz
uspto-grants-1988_06
Patentnummer
US04751232

Verknüpfte Notizen

Wird geladen…