Benzene, [1-[(trimethylsilyl)oxy]ethenyl]- → 2-Phenylacetophenone

Temperatur

0 °C

0.97 mmol of (1-phenylethenyl)oxytrimethylsilane was placed in a 20-ml flask, followed by the addition of 3 ml of pyridine as a solvent. 1.3 mmol of benzenediazonium tetrafluoroborate was added to the flask. The resulting mixture was stirred at 0° C. in a nitrogen atmosphere for 2 hours. The reaction mixture was diluted with diethyl ether and washed with 1.5N hydrochloric acid, water and a saturated aqueous solution of a common salt, successively. The organic phase was dried over magnesium sulfate and distilled under a reduced pressure to remove the solvent. The obtained oily mixture was subjected to silica gel thin-layer chromatography to obtain 0.68 mmol of benzyl phenyl ketone.

1. washwashed with 1.5N hydrochloric acid, water
2. dry with materialThe organic phase was dried over magnesium sulfate
3. distillationdistilled under a reduced pressure
4. customto remove the solvent

ORD-Eintrag

ord-62b15808900d478c86f8bda1ba4381fa

Quelldatensatz

uspto-grants-1988_09

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US04772714