Water → 5-bromo-2-hydroxy-4-methylbenzoic acid

HRID 629330Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 629330
[OH:1][C:2]1[CH:10]=[C:9]([CH3:11])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[Br:12]Br.O>C(O)(=O)C>[Br:12][C:8]1[C:9]([CH3:11])=[CH:10][C:2]([OH:1])=[C:3]([CH:7]=1)[C:4]([OH:6])=[O:5]

Komponenten

5

Edukt 3

HCID 962WaterHCID 57882-Hydroxy-p-toluic acidHCID 24408Bromine

Produkt 1

HCID 2439345-bromo-2-hydroxy-4-methylbenzoic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

To a solution of 2-hydroxy-4-methylbenzoic acid (5.00 g) in acetic acid (70.0 mL) was added dropwise bromine (1.68 mL), and the mixture was stirred at room temperature for 5.5 hr. To the reaction mixture was added water, and the precipitate was collected by filtration, and dried under reduced pressure to give the title compound (6.78 g).

Aufarbeitung

  1. filtrationthe precipitate was collected by filtration
  2. customdried under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-33f50400cbf0496d9ad10fd87bd16de3
Quelldatensatz
uspto-grants-2016_04
Patentnummer
US09315458B2

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