Itaconic acid → 3-(Benzothiazol-2-ylthio)-propane-1,2-dicarboxylic acid

HRID 65123

Reaktionsgleichung

Reaktionsgleichung von HRID 65123
[Al+3].[Cl-].[Cl-].[Cl-].[SH:5][C:6]1[S:7][C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[N:10]=1.[C:15]([OH:23])(=[O:22])[C:16]([CH2:18][C:19]([OH:21])=[O:20])=[CH2:17].O>C(OCC)C.C(OCC)(=O)C>[S:7]1[C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[N:10]=[C:6]1[S:5][CH2:17][CH:16]([C:15]([OH:23])=[O:22])[CH2:18][C:19]([OH:21])=[O:20]

Komponenten

7

Edukt 4

HCID 811Itaconic acidHCID 962WaterHCID 6451240Aluminum(III) ChlorideHCID 178418395HCID 178418395, Verbindung

Produkt 1

HCID 194275373-(Benzothiazol-2-ylthio)-propane-1,2-dicarboxylic acidAusbeute 50,5 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 3283Diethyl EtherLösungsmittel2×HCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

13.3 g of AlCl3 are dissolved in 100 ml of diethyl ether at 0° to 5°. 3.4 g of 2-mercaptobenzothiazole and 2.6 g of itaconic acid are then added. After the mixture has been stirred at 20°-25° for 24 hours, the ether solution is poured off and the residue is stirred with 100 ml of water and 100 ml of ethyl acetate. The organic phase is separated off, dried and evaporated. 3 g of 3-(benzothiazol-2-ylthio)-propane-1,2-dicarboxylic acid are obtained as the residue.

Aufarbeitung

  1. customThe organic phase is separated off
  2. customdried
  3. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-7b1fd30bd3da47a381b20f84f472db06
Quelldatensatz
uspto-grants-1986_09
Patentnummer
US04612378

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