Acetic Anhydride → [5-[4-(Dimethylamino)butyl]-2-furanyl]methyl ethanoate

HRID 65738Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 65738
[CH3:1][N:2]([CH3:14])[CH2:3][CH2:4][CH2:5][CH2:6][C:7]1[O:11][C:10]([CH2:12][OH:13])=[CH:9][CH:8]=1.[C:15](OC(=O)C)(=[O:17])[CH3:16].C([O-])(=O)C.[Na+]>C1C=CC=CC=1.O>[C:15]([O:13][CH2:12][C:10]1[O:11][C:7]([CH2:6][CH2:5][CH2:4][CH2:3][N:2]([CH3:1])[CH3:14])=[CH:8][CH:9]=1)(=[O:17])[CH3:16]

Komponenten

6

Edukt 3

HCID 7918Acetic AnhydrideHCID 517045Sodium AcetateHCID 23452131HCID 23452131, Verbindung

Produkt 1

HCID 23452115[5-[4-(Dimethylamino)butyl]-2-furanyl]methyl ethanoate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 241BenzeneLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 5-[4-(dimethylamino)butyl]-2-furanmethanol (4.9 g), acetic anhydride (25 g) and fused and powdered sodium acetate (10 g) in benzene (25 ml) was stirred at room temperature for 24 hr. The reaction was diluted with water (100 ml) and extracted with ethyl acetate. The combined extracts were distilled to afford a clear colourless oil b.p. 100°, 0.5 mm Hg. Found: C, 65.62; H, 9.03; N, 5.95. Calc. for C13H21NO3 : C, 65.24; H, 8.85; N, 5.85%.

Aufarbeitung

  1. extractionextracted with ethyl acetate
  2. distillationThe combined extracts were distilled

Quellen und Nachweise

ORD-Eintrag
ord-c2378da5ae4843158432c6149734716a
Quelldatensatz
uspto-grants-1978_12
Patentnummer
US04128658

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