Hydrochloric Acid → HCID 21950839, Verbindung

HRID 848833Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 848833
Cl[C:2]1[CH:15]=[CH:14][C:5]([C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:7])=[CH:4][CH:3]=1.[SH:16][CH2:17][CH2:18][OH:19].C([O-])([O-])=O.[K+].[K+].Cl>CCOCC.O.CC(CC)=O>[OH:19][CH2:18][CH2:17][S:16][C:2]1[CH:15]=[CH:14][C:5]([C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:7])=[CH:4][CH:3]=1

Komponenten

8

Edukt 4

HCID 313Hydrochloric AcidHCID 15672-MercaptoethanolHCID 86534-ChlorobenzophenoneHCID 11430Potassium Carbonate

Produkt 1

HCID 21950839HCID 21950839, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 962WaterLösungsmittelHCID 3283Diethyl EtherLösungsmittelHCID 6569Methyl Ethyl KetoneLösungsmittel

Versuchsvorschrift

11.2 g (0.05 mol) of 4-chlorobenzophenone, 4.3 g (0.055 mol) of 2-mercaptoethanol, 13.8 g (0.1 mol) of calcined K2CO3 and 15 ml of ethyl methyl ketone are warmed (under reflux) for 16 hours under nitrogen. 50 ml of water are poured over the cooled reaction mixture and the resulting mixture is acidified with HCl. The product is taken up in ether. The ether layer is washed with water, dried over Na2SO4 and concentrated. The product, which in this case also is obtained as an oil, crystallises on standing. It is boiled up in hexane as described in (a). Yield: 10.0 g (77%). Melting point 49°-51°.

Aufarbeitung

  1. temperature(under reflux) for 16 hours under nitrogen
  2. washThe ether layer is washed with water
  3. dry with materialdried over Na2SO4
  4. concentrationconcentrated
  5. customThe product, which in this case also is obtained as an oil
  6. customcrystallises

Quellen und Nachweise

ORD-Eintrag
ord-9941b0fc29e94f388b43e9e54f2d37fe
Quelldatensatz
uspto-grants-1981_10
Patentnummer
US04297513

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