Methane → HCID 131720463, Verbindung

HRID 861996Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 861996
[CH2:1]([O:3][P:4]([O:20][CH2:21][CH3:22])([C:6]1[N:11]2[CH:12]=[C:13]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[N:14]=[C:10]2[CH:9]=[CH:8][CH:7]=1)=[O:5])[CH3:2].C.P(CC1C2N(C=C(C(O)=O)N=2)C=CC=1)(O)(O)=O.O1CCOCC1.[Cl:47]Cl>CCOCC>[ClH:47].[CH2:1]([O:3][P:4]([O:20][CH2:21][CH3:22])([C:6]1[N:11]2[CH:12]=[C:13]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[N:14]=[C:10]2[CH:9]=[CH:8][CH:7]=1)=[O:5])[CH3:2]

Komponenten

7

Edukt 5

HCID 297MethaneHCID 24526ChlorineHCID 312751,4-DioxaneHCID 19701110Ethyl 5-(diethoxyphosphinyl)imidazo[1,2-a]pyridine-2-carboxylateHCID 19701381HCID 19701381, Verbindung

Produkt 1

HCID 131720463HCID 131720463, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

The product from Example 51 (1.6 g, 4.4 mmol) was dissolved in CH2 Cl2 (30 mL), treated with activated charcoal and filtered. To this filtrate was then added 6N HCl in dioxane (0.9 mL, 4.4 mmol) followed by Et2O (100 mL). The precipitated product was filtered, washed with Et2O, and dried in vacuo.

Aufarbeitung

  1. filtrationfiltered
  2. filtrationThe precipitated product was filtered
  3. washwashed with Et2O
  4. customdried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-756be3881f944587ac22bb3e422c4239
Quelldatensatz
uspto-grants-1998_02
Patentnummer
US05716964

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