Chlorodiisopropylphosphine → HCID 178460690, Verbindung

HRID 925042

Reaktionsgleichung

Reaktionsgleichung von HRID 925042
[C:1]([C:5]1[CH:23]=[CH:22][C:8]([C:9]([NH:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[C:18]([CH3:21])([CH3:20])[CH3:19])=[NH:10])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].C([Li])CCC.Cl[P:30]([CH:34]([CH3:36])[CH3:35])[CH:31]([CH3:33])[CH3:32]>>[C:1]([C:5]1[CH:23]=[CH:22][C:8]([C:9]([NH:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[C:18]([CH3:21])([CH3:20])[CH3:19])=[N:10][P:30]([CH:34]([CH3:36])[CH3:35])[CH:31]([CH3:33])[CH3:32])=[CH:7][CH:6]=1)([CH3:4])([CH3:2])[CH3:3]

Komponenten

4

Edukt 3

HCID 538967ChlorodiisopropylphosphineHCID 178418339ButyllithiumHCID 178440935HCID 178440935, Verbindung

Produkt 1

HCID 178460690HCID 178460690, Verbindung

Versuchsvorschrift

Procedure as described for NP Amidine I using the following amounts: 1.54 g of 4-tert-butyl-N1-(2-tert-butylphenyl)benzamidine (Amidine VII, 5.0 mmol), 2.50 mL of 2.0 M butyllithium (5.0 mmol), 0.80 mL chlorodiisopropylphosphine (5.0 mmol). After filtration to remove lithium chloride and removal of solvent, a yellow semi-solid was isolated (1.9 g, 100%).

Aufarbeitung

  1. filtrationAfter filtration
  2. customto remove
  3. customlithium chloride and removal of solvent
  4. customa yellow semi-solid was isolated (1.9 g, 100%)

Quellen und Nachweise

ORD-Eintrag
ord-a7d2b1ae01704f778ef8d11870c35a07
Quelldatensatz
uspto-grants-2016_03
Patentnummer
US09283555B2

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