Basic information
- CAS
10034-99-8- Standard SMILES
O.O.O.O.O.O.O.O=S(=O)([O-])[O-].[Mg+2]- InChIKey
WRUGWIBCXHJTDG-UHFFFAOYSA-L- Molecular formula
- Mg.S.O4.7H2O
- Average molar mass
- 246.48 g/mol
- Monoisotopic mass
- 246.01072397
Overview
Magnesium sulfate heptahydrate is a hydrate that is the heptahydrate form of magnesium sulfate. It has a role as a laxative and a cathartic. It is a magnesium salt and a hydrate. It contains a magnesium sulfate.
Names & identifiers
- Preferred name
- Magnesium Sulfate Heptahydrate
- IUPAC
- magnesium;sulfate;heptahydrate
- English name
- Magnesium sulfate heptahydrate
- Molecular formula
- Mg.O4S.7H2O
- Molecular weight
- 246.47
Names & synonyms
Show more names
Database identifiers
- CAS
10034-99-8、14457-55-7- PubChem CID
- 24843
- DTXSID
DTXSID5040544- ChEBI
CHEBI:31795- UNII
- SK47B8698T
- EC Number
- 600-073-4、913-387-4
Properties
Computed structural properties
- Topological polar surface area
- 95.6 Ų
- Hydrogen bond donors
- 7
- Hydrogen bond acceptors
- 11
- Rotatable bonds
- 0
- Heavy atoms
- 13
- Formal charge
- 0
- Complexity
- 62.2
Experimental & physicochemical properties
Physicochemical properties
- Melting point
- 1124 °C · 1124°C
- Density
- 2.66 · 2.66
- bulk density
- 900 kg/m3 · 900kg/m3
- vapor density
- 0.01 · <0.01 (vs air)
- vapor pressure
- 0.1 mm · <0.1 mm Hg ( 20 °C)
- refractive index
- 1.433 · 1.433
- storage temp.
- 5 °C · Store at +5°C to +30°C.
- solubility
- 2 O: · H2O: 1 M at 20 °C, clear, colorless
- form
- Solid
- Specific Gravity
- 1.68 · 1.68
- color
- White
- PH
- 5 · 5.0-8.0 (25℃, 50mg/mL in H2O)
- Odor
- Odorless
- Water Solubility
- Soluble in in water and acid. Slightly soluble in alcohol and glycerol.
- λmax
- 260 nm · λ: 260 nm Amax: 0.010λ: 280 nm Amax: 0.010
- Merck
- 14 · 14,5691
- Dielectric constant
- 8.2 · 8.2(Ambient)
- Stability
- Stable. Non-flammable. May slowly deteriorate in contact with air.
- Cosmetics Ingredients Functions
- BULKING
- InChI
- 1S/Mg.H2O4S.7H2O/c;1-5(2,3)4;;;;;;;/h;(H2,1,2,3,4);7*1H2/q+2;;;;;;;;/p-2
- InChIKey
- WRUGWIBCXHJTDG-UHFFFAOYSA-L
- SMILES
- O.O.O.O.O.O.O.[Mg++].[O-]S([O-])(=O)=O
- LogP
- -1.031 · -1.031 (est)
- CAS DataBase Reference
- 10034 · 10034-99-8(CAS DataBase Reference)
- Substances Added to Food (formerly EAFUS)
- MAGNESIUM SULFATE
- FDA 21 CFR
- 310.545 · 310.545; 558.311
- SCOGS (Select Committee on GRAS Substances)
- Magnesium sulfate
- EWG's Food Scores
- 1 · 1
- NCI Dictionary of Cancer Terms
- magnesium sulfate
- FDA UNII
- 47 B8698T · SK47B8698T
- ATC code
- 6 AD04,A12CC02,B05XA05,D11AX05,V04CC02 · A06AD04,A12CC02,B05XA05,D11AX05,V04CC02
- NIST Chemistry Reference
- magnesium sulfate heptahydrate(10034-99-8)
- EPA Substance Registry System
- Magnesium sulfate heptahydrate (10034-99-8)
- UNSPSC Code
- 41116107 · 41116107
- NACRES
- 24 · NB.24
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
- Hazard Codes
- Xi
- Risk Statements
- 36 · 36/37/38
- Safety Statements
- 24 · 24/25-36-26
- WGK Germany
- 1 · 1
- RTECS
- 4508000 · OM4508000
- TSCA
- Yes
- HS Code
- 28332100 · 28332100
- Storage Class
- 13 · 13 - Non Combustible Solids
- Toxicity
- 183 mg/kg/4H-I · man,TDLo,oral,183mg/kg/4H-I (183mg/kg),GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA",Journal of Toxicology, Clinical Toxicology. Vol. 20, Pg. 107, 1983.
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 100% (424 of 424) of all reports.
Not Classified
Aggregated GHS information provided per 424 reports by companies from 2 notifications to the ECHA C&L Inventory.
This chemical does not meet GHS hazard criteria for 100% (2 of 2) of all reports.
Not Classified
Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory Information
Chemical: Sulfuric acid, magnesium salt, heptahydrate
Sulfuric acid magnesium salt (1:1), heptahydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Sulfuric acid magnesium salt (1:1), heptahydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Sulfuric acid magnesium salt (1:1), heptahydrate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and Categories
Not Classified
Not Classified
Safety & protection
Protective Action Criteria (PAC)
1.2 [mg/m3]
13 [mg/m3]
81 [mg/m3]
Safety data
- wgk
- 1
- tsca
- Yes
- rtecs
- OM4508000
- hs_code
- 28332100
- Toxicity
- man,TDLo,oral,183mg/kg/4H-I (183mg/kg),GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA",Journal of Toxicology, Clinical Toxicology. Vol. 20, Pg. 107, 1983.
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 24/25-36-26
- Storage Class
- 13 - Non Combustible Solids
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Chemistry & industry
Pharmacology
FDA Pharmacological Classification
50% MAGNESIUM SULFATE
Increased Large Intestinal Motility [PE]; Stimulation Large Intestine Fluid/Electrolyte Secretion [PE]; Inhibition Small Intestine Fluid/Electrolyte Absorption [PE]; Magnesium Ion Exchange Activity [MoA]; Osmotic Laxative [EPC]; Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Activity [MoA]; Calculi Dissolution Agent [EPC]
EPSOM SALT
Calculi Dissolution Agent [EPC]; Osmotic Activity [MoA]; Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Laxative [EPC]; Magnesium Ion Exchange Activity [MoA]; Inhibition Small Intestine Fluid/Electrolyte Absorption [PE]; Stimulation Large Intestine Fluid/Electrolyte Secretion [PE]; Increased Large Intestinal Motility [PE]
MAGNESIA SULPHURICA
Calculi Dissolution Agent [EPC]; Osmotic Activity [MoA]; Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Laxative [EPC]; Magnesium Ion Exchange Activity [MoA]; Inhibition Small Intestine Fluid/Electrolyte Absorption [PE]; Stimulation Large Intestine Fluid/Electrolyte Secretion [PE]; Increased Large Intestinal Motility [PE]
MeSH Pharmacological Classification
Compounds capable of relieving pain without the loss of CONSCIOUSNESS.
Agents capable of inducing a total or partial loss of sensation, especially tactile sensation and pain. They may act to induce general ANESTHESIA, in which an unconscious state is achieved, or may act locally to induce numbness or lack of sensation at a targeted site.
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
Drugs used to prevent SEIZURES or reduce their severity.
A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
Drugs that prevent preterm labor and immature birth by suppressing uterine contractions (TOCOLYSIS). Agents used to delay premature uterine activity include magnesium sulfate, beta-mimetics, oxytocin antagonists, calcium channel inhibitors, and adrenergic beta-receptor agonists. The use of intravenous alcohol as a tocolytic is now obsolete.
Uses & manufacturing
Use Classification
EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives
Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern
Applications
Uses1. It can be used for catharsis with its saturated solution subject to topical administration. It has anti-inflammatory, detumescence, detoxification, analgesic effect, and can inhibit the effect of central nervous system, anti-traction and antispasmodic; used as the weighing agent of printing fine cotton, cotton, silk and the filler for kapok products; it can be used for the manufacturing of grass, fertilizers, porcelain, pigments, matches, explosives and fireproof materials; can be used as the medium component in the microbial industry; supplying the magnesium for brewing additives; used as filler to enhance the thermal resistance in the leather industry; used for the production of fresh yeast, monosodium glutamate and the stabilizer of dicalcium phosphate used in toothpaste production; can also be used in cement coagulant; pulp industry, rayon and silk industry, etc. Product containing a small amount of crystal water or no crystal water can be used for the synthesis of product that contains low water content and mixed ingredients. In organic chemical industry, it can be used for desiccant and dehydrating agent for printing thin cotton, silk, as the aggravating agent of cotton and filler of kapok products. 2. It can be used for leather industry, fertilizer, porcelain, matches, explosives, printing and dyeing, pharmaceutical and other industries 3. It can be used for steelmaking and ironmaking 4. Magnesium sulfate is a feed nutrition enhancer. 5. It can be used as laxative, cholagogue, for cathartic and duodenal diversion 6. It can be used as analysis reagents and mordant 7. It can be used as food fortifier. China provides that it can be used for dairy products with the usage amount of 3~7 g/kg; usage amount in the beverages and milk beverages is 1.4~2.8g/kg; the maximum dose in mineral drinks should be 0.05g/kg. 8. It can be used as nutritional supplements, curing agents, flavor enhancers, processing aids. Brewing additives for supplement the magnesium of brewing water; as a source of nutrients during fermentation to enhance the fermentation capacity; improve the flavor of synthetic wine (usage amount of 0.002%). Adjust the water hardness. In Europe for the production of "Bolton" type of beer. 9. It is often used in combination with the calcium salt for the yeast-purpose water. Addition of 4.4g/100 water being able to increase the hardness of 1 degree with multi-use producing bitter and producing hydrogen sulfide odor. 10. This product can be used as tanning filler. In the printing and dyeing industry, it can be used as the aggravating agent of the thin cotton. Used as paper sizing agent. 11. U
DescriptionIn addition to its use in foods as a flavor enhancer, nutrient supplement and processing aid, magnesium sulfate (as Epsom salt) is employed in over-the-counter preparations as a laxative. As a legend (prescription drug) it has been used as an anticonvulsant and electrolyte replenisher.
UsesUsed in preparation of magnesium standard solutions
UsesMagnesium Sulfate is a nutrient and dietary supplement. It is soluble in water and its solutions are neutral. It exists as crystals with a cooling, saline, bitter taste. It is also termed epsom salt.
UsesMagnesium sulfate heptahydrate has been used:as a component in Kreb′s Ringer bufferas a component in minimal medium to culture Ralstonia solanacearumin the preparation of maceration solution for Lamb′s lettuce cell isolation and isotonic glucose buffer
General DescriptionMagnesium sulfate heptahydrate is hydroscopic and is vulnerable to warm temperatures.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers100 total
Additional notes
DefinitionEpsomite: a mineral form of magnesiumsulphate heptahydrate,MgSO4.7H2O.
Related reactions
Compound notes
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