Tetrahydrofuran → methyl 2-[(tetrahydropyran-4-yl)oxy]-6,7-dihydro-5H-benzocycloheptene-8-carboxylate

HRID 100107

Reaction equation

HRID 100107 reaction equation
[CH2:57]1[O:58][CH2:59][CH2:60][CH2:61]1.[O:20]1[CH2:21][CH2:22][CH:23]([OH:26])[CH2:24][CH2:25]1.[O:43]=[C:44]([O:45][CH:46]([CH3:47])[CH3:48])[N:49]=[N:50][C:51]([O:52][CH:53]([CH3:54])[CH3:55])=[O:56].[OH:27][c:28]1[cH:29][cH:30][c:31]2[c:32]([cH:42]1)[CH:33]=[C:34]([C:38](=[O:39])[O:40][CH3:41])[CH2:35][CH2:36][CH2:37]2.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[O:20]1[CH2:21][CH2:22][CH:23]([O:26][c:28]2[cH:29][cH:30][c:31]3[c:32]([cH:42]2)[CH:33]=[C:34]([C:38](=[O:39])[O:40][CH3:41])[CH2:35][CH2:36][CH2:37]3)[CH2:24][CH2:25]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 74956Tetrahydro-4H-pyran-4-olHCID 75555Diisopropyl diazene-1,2-dicarboxylateHCID 22989944methyl 2-hydroxy-6,7-dihydro-5H-benzocycloheptene-8-carboxylate

Product 1

HCID 22989939methyl 2-[(tetrahydropyran-4-yl)oxy]-6,7-dihydro-5H-benzocycloheptene-8-carboxylate

Sources & evidence

ORD record
ord-086f8070fcd84497bed3eacdc2beb614
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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