Dimethylformamide → 6-[(1-Methyl-4-phenyl-1H-imidazol-5-yl)ethynyl]pyrimidine-4,5-diamine

HRID 100599

Reaction equation

HRID 100599 reaction equation
[C:10](#[CH:11])[c:12]1[c:13](-[c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[n:14][cH:15][n:16]1[CH3:17].[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[Cu:36][I:37].[I:1][c:2]1[c:3]([NH2:9])[c:4]([NH2:8])[n:5][cH:6][n:7]1.[O:31]=[CH:32][N:33]([CH3:34])[CH3:35]>>[c:2]1([C:11]#[C:10][c:12]2[c:13](-[c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[n:14][cH:15][n:16]2[CH3:17])[c:3]([NH2:9])[c:4]([NH2:8])[n:5][cH:6][n:7]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 179658065-Ethynyl-1-methyl-4-phenyl-1H-imidazoleHCID 179658946-Iodopyrimidine-4,5-diamine

Product 1

HCID 179657996-[(1-Methyl-4-phenyl-1H-imidazol-5-yl)ethynyl]pyrimidine-4,5-diamine

Sources & evidence

ORD record
ord-e42540141bcc493ea2c07a4c24ae44e3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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