Dimethylformamide → 1,6-Dihydro-1-(4-methyl-2-pyridinyl)-6-oxo-3-pyridinecarbonitrile

HRID 101647

Reaction equation

HRID 101647 reaction equation
[CH3:12][c:13]1[cH:14][c:15](-[n:19]2[cH:20][c:21]([C:26](=[O:27])[NH2:28])[cH:22][cH:23][c:24]2=[O:25])[n:16][cH:17][cH:18]1.[CH3:1][N:2]([CH3:3])[CH:4]=[O:5].[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[CH3:36][C:37]#[N:38].[Cl:6][C:7]([C:8]([Cl:9])=[O:10])=[O:11]>>[CH3:12][c:13]1[cH:14][c:15](-[n:19]2[cH:20][c:21]([C:26]#[N:28])[cH:22][cH:23][c:24]2=[O:25])[n:16][cH:17][cH:18]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 6342AcetonitrileHCID 8471TriethylamineHCID 65578Oxalyl chlorideHCID 223436911,6-Dihydro-1-(4-methyl-2-pyridinyl)-6-oxo-3-pyridinecarboxamide

Product 1

HCID 223440771,6-Dihydro-1-(4-methyl-2-pyridinyl)-6-oxo-3-pyridinecarbonitrile

Sources & evidence

ORD record
ord-7c8b226f0c914d14b8683cf55004191d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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