4-Amino-1-pentofuranosyl-2(1H)-pyrimidinone → 5-(Trifluoromethyl)cytidine
Reaction equation
[CH3:31][S:32](=[O:33])[CH3:34].[F:18][C:19]([F:20])([F:21])[I:22].[Fe+2:30].[NH2:1][c:2]1[cH:3][cH:4][n:5]([CH:6]2[O:7][CH:8]([CH2:9][OH:10])[CH:11]([OH:12])[CH:13]2[OH:14])[c:15](=[O:16])[n:17]1.[OH:23][OH:24].[S:25]([O-:26])([O-:27])(=[O:28])=[O:29]>>[NH2:1][c:2]1[c:3]([C:19]([F:18])([F:20])[F:21])[cH:4][n:5]([CH:6]2[O:7][CH:8]([CH2:9][OH:10])[CH:11]([OH:12])[CH:13]2[OH:14])[c:15](=[O:16])[n:17]1Participants
7
Sources & evidence
- ORD record
- ord-3f33187b60294964bcdef3650482190e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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