Sodium Ion → [4-(5-Bromo-pyrimidin-2-ylamino)-phenyl]-methanol

Reaction equation

[Br:10][c:11]1[cH:12][n:13][c:14]([Cl:17])[n:15][cH:16]1.[CH3:29][CH:30]([OH:31])[CH3:32].[CH:20]([N:21]([CH:22]([CH3:23])[CH3:24])[CH2:25][CH3:26])([CH3:27])[CH3:28].[I-:19].[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][OH:7])[cH:8][cH:9]1.[Na+:18]>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([CH2:6][OH:7])[cH:8][cH:9]1)[c:14]1[n:13][cH:12][c:11]([Br:10])[cH:16][n:15]1

Participants

Reactant 6

HCID 923Sodium Ion

HCID 3776Isopropanol

HCID 30165Iodide Ion

HCID 693314-Aminobenzyl alcohol

HCID 81531Diisopropylethylamine

HCID 6066655-Bromo-2-chloropyrimidine

Product 1

HCID 57632949[4-(5-Bromo-pyrimidin-2-ylamino)-phenyl]-methanol

Sources & evidence

ORD record: ord-4f40ef4da2ca49e591592ad1c7462097
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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