Ammonium → Ethyl 5-ethylthiophene-3-carboxylate

Reaction equation

[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([NH2:13])[s:8][c:9]([CH2:11][CH3:12])[cH:10]1.[CH3:23][CH2:24][OH:25].[Cl-:21].[Cu:26]([Br:27])[Br:28].[N:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20].[NH4+:22]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][s:8][c:9]([CH2:11][CH3:12])[cH:10]1

Participants

Reactant 6

HCID 223Ammonium

HCID 312Chloride

HCID 702Ethanol

HCID 10906Tert-Butyl nitrite

HCID 24611Copper bromide (CuBr2)

HCID 78263Ethyl 2-amino-5-ethyl-3-thenoate

Product 1

HCID 12588559Ethyl 5-ethylthiophene-3-carboxylate

Sources & evidence

ORD record: ord-63c1ec2711af4f4f8e34a46e72cdc3fb
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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