Epichlorohydrin → 3-(1-Bromonaphth-2-yloxy)-1,2-epoxypropane
Reaction equation
[Br:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[OH:12].Cl[CH2:14][CH:15]1[O:17][CH2:16]1.C(=O)([O-])[O-].[K+].[K+]>CC(=O)CC>[Br:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[O:12][CH2:14][CH:15]1[O:17][CH2:16]1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
A suspension containing 22.3 g of 1-bromonaphth-2-ol, 27.75 g of 1-chloro-2,3-epoxypropane and 27.6 g of potassium carbonate in 200 ml of butanone is refluxed overnight. The inorganic salts are filtered off and drained and the filtrate is then evaporated under vacuum. The oil obtained is distilled under 0.01 mm of mercury.
Workup
- temperatureis refluxed overnight
- filtrationThe inorganic salts are filtered off
- customthe filtrate is then evaporated under vacuum
- customThe oil obtained
- distillationis distilled under 0.01 mm of mercury
Sources & evidence
- ORD record
- ord-e743b44489f04654891d9a3d50b33511
- Source dataset
- uspto-grants-1991_07
- Patent number
- US05036077
Reaction notes
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