Chloride → 1-(2-Hydroxyethyl)-3,3-diphenylpyrrolidin-2-one

Reaction equation

[CH3:23][CH2:24][O:25][C:26](=[O:27])[CH3:28].[Cl-:29].[Cl-:31].[NH2:19][CH2:20][CH2:21][OH:22].[Zn+2:30].[c:1]1([C:7]2([c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[C:8](=[O:12])[O:9][CH2:10][CH2:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([C:7]2([c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[C:8](=[O:9])[N:19]([CH2:20][CH2:21][OH:22])[CH2:10][CH2:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

Reactant 5

HCID 312Chloride2×

HCID 700Ethanolamine

HCID 8857Ethyl Acetate

HCID 32051Zinc(2+)

HCID 70393Dihydro-3,3-diphenyl-2(3H)-furanone

Product 1

HCID 673575371-(2-Hydroxyethyl)-3,3-diphenylpyrrolidin-2-one

Sources & evidence

ORD record: ord-4085ec61574645e0962c67f08658bb3d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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